| Category |
Efficacy service |
Test Period |
Skin irritation
(Erythema, inflammation)
|
- Cytotoxicity assay
- Antioxidant test (DPPH, SOD, Lipid peroxidation assay, Nitric oxide, ROS)
- Inflammatory cytokine assay (TNF-α, IL-8, COX-2, Eotaxin-1)
|
4-6 weeks after the products reception |
Pigmentation disorder
(Melasma, hyperpigmentation, vitiligo)
|
- Mushroom tyrosinase activity assay
- Cellular tyrosinase activity assay
- Melanin contents assay
|
4-6 weeks after the products reception |
Skin-ageing
(Wrinkle, Stem cell, photoageing)
|
- Cell proliferation (skin self-renewal)
- ECM production (collagen, elastin, Hyaluronic acid)
- DNA damage assay (UV radiation and Oxidative stress)
- AGEs production assay
- Cellular senescence assay (SA-beta-Gal assay)
|
4-6 weeks after the products reception |
Inflammatory skin
(Atopy, psoriasis, acne, seborrhea dermatitis) |
- Immune regulation : IL-2
- Inflammatory cytokine assay (TNF-α, IL-1, IL-4, IL-8, COX-2, Eotaxin-1)
- NF-κB luciferase activity assay
|
4-6 weeks after the products reception |
Infection
(Acne, dandruff, athletes foot, atopy) |
- Disk diffusion test(P.acne, P.ovale, S.aureus, P.aeruginosa, E.coli, C.albican, etc,)
- MIC test(Determination of minimal inhibition concentration)
- Challenge Test(Gram +/Gram -, Yeast, Fungi)
|
4-8 weeks after the products reception |
Obesity
(Sliming)
|
-oil-red O staining/Tri-glyceride assay
-Lipolysis(Glycerol release assay)
-GPDH activity inhibition assay
|
4-8 weeks after the products reception |
| Hair |
- Hair follicle dermal papilla cell proliferation
- Keratinocytes proliferation
|
4-8 weeks after the products reception |
| Toxicology test |
- Phototoxicity test(3T3NRU phototoxicity test)
- Eye irritation (HET-CAM)
|
4-6 weeks after the products reception |
