| >> INCI Name & the Plant
Source |
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INCI Name: Oleanolic acid, Lecithin, Butylene Glycol
Plant Source: Olive
leaf (Olea europaea) |
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| >> Claims on NLT OASphere
1.0™ |
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Nano-sized liposome containing 1% of oleanolic acid
Anti-microbial and
anti-viral
Anti-oxidantion |
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| >> Main Active Ingredient of NLT
OASphere 1.0™ is Oleuropein |
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| The bitter compound oleuropein, the major constituent of the secoiridoid
family in the olive (Olea europaea L.) trees, has been shown to be a potent
antioxidant endowed with anti-inflammatory. In 1970 diverse papers showed the
antiviral and bactericide activity of calcium elenolate (obtained by hydrolysis
of oleuropein). Posterior report demonstrated that oleuropein also had
anti-microbial activity against viruses, retroviruses, bacterium, yeasts, fungi,
molds and other parasites. Other clinical effects of oleuropein were the
potentiation of cellular and organismal protection through the
macrophage-mediated response, the inhibition of platelet aggregation and
eicosanoid production and the reduction of the LDL level (the bad cholesterol)
for about 30%. Clinical experiences showed that supplemental oleuropein (as
olive leaf extract) might be beneficial as healing participant in the treatment
of a variety of infectious and chronic diseases, such as: flu-like symptoms and
colds, pneumonia, gonorrhoea, etc. These properties joined to their
anti-microbial activity make of olive leaf extract an extremely suitable
component of cosmetic preparation where it can act as anti-aging and
bacteriostatic agent. |
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| >> Physical Properties of NLT
OASphere 1.0™ |
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| >> Stability of NLT OASphere
1.0™ |
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| Shelf-life of 1 year before opening |
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| >> Scientific Study: Anti-Microbial
Effect of NLT OASphere 1.0™ |
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| >> Scientific Study: Anti-Viral
Effect of NLT OASphere 1.0™ |
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a) IC50 is the concentration of the sample required to inhibit virus-induced
CPE 50%.
b) TC50 is the concentration of the 50% cytotoxic effect.
c)
TI=TC50/IC50.
d) Ribavirin, an approved drug for treatment of RSV
infections. |
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